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Allergic sensitization

MedGen UID:
783637
•Concept ID:
C3662483
•
Disease or Syndrome
SNOMED CT: Allergic sensitization (609327009)

Definition

A process characterised by an initial humoral or cell-mediated immune response to a foreign antigen resulting in the production of specific antibodies and/or immune cells which may then lead to an allergic disposition. [from SNOMEDCT_US]

Professional guidelines

PubMed

Advances in the Assessment and Management of Allergic Sensitization.
Sampson HA, Hamilton RG
J Allergy Clin Immunol Pract 2023 Oct;11(10):3008-3009. Epub 2023 Aug 22 doi: 10.1016/j.jaip.2023.08.023. PMID: 37611661
Biologics in the treatment of asthma in children and adolescents.
Bacharier LB, Jackson DJ
J Allergy Clin Immunol 2023 Mar;151(3):581-589. Epub 2023 Jan 24 doi: 10.1016/j.jaci.2023.01.002. PMID: 36702649
A Current Perspective of Allergic Asthma: From Mechanisms to Management.
Papadopoulos NG, Miligkos M, Xepapadaki P
Handb Exp Pharmacol 2022;268:69-93. doi: 10.1007/164_2021_483. PMID: 34085124

Recent clinical studies

Etiology

A Current Perspective of Allergic Asthma: From Mechanisms to Management.
Papadopoulos NG, Miligkos M, Xepapadaki P
Handb Exp Pharmacol 2022;268:69-93. doi: 10.1007/164_2021_483. PMID: 34085124
Allergic Rhinitis in Children and Adolescents.
Schuler Iv CF, Montejo JM
Pediatr Clin North Am 2019 Oct;66(5):981-993. Epub 2019 Aug 5 doi: 10.1016/j.pcl.2019.06.004. PMID: 31466686
Food Allergen Epitope Mapping.
Liu C, Sathe SK
J Agric Food Chem 2018 Jul 18;66(28):7238-7248. Epub 2018 Jul 9 doi: 10.1021/acs.jafc.8b01967. PMID: 29924613
Predicting asthma outcomes.
Sears MR
J Allergy Clin Immunol 2015 Oct;136(4):829-36; quiz 837. doi: 10.1016/j.jaci.2015.04.048. PMID: 26449797
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351

Diagnosis

Allergic Rhinitis in Children and Adolescents.
Schuler Iv CF, Montejo JM
Immunol Allergy Clin North Am 2021 Nov;41(4):613-625. doi: 10.1016/j.iac.2021.07.010. PMID: 34602232
Clinical Relevance of Cross-Reactivity in Food Allergy.
Cox AL, Eigenmann PA, Sicherer SH
J Allergy Clin Immunol Pract 2021 Jan;9(1):82-99. doi: 10.1016/j.jaip.2020.09.030. PMID: 33429724
Allergic Rhinitis in Children and Adolescents.
Schuler Iv CF, Montejo JM
Pediatr Clin North Am 2019 Oct;66(5):981-993. Epub 2019 Aug 5 doi: 10.1016/j.pcl.2019.06.004. PMID: 31466686
Food allergies: the basics.
Valenta R, Hochwallner H, Linhart B, Pahr S
Gastroenterology 2015 May;148(6):1120-31.e4. Epub 2015 Feb 11 doi: 10.1053/j.gastro.2015.02.006. PMID: 25680669Free PMC Article
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351

Therapy

Biologics in the treatment of asthma in children and adolescents.
Bacharier LB, Jackson DJ
J Allergy Clin Immunol 2023 Mar;151(3):581-589. Epub 2023 Jan 24 doi: 10.1016/j.jaci.2023.01.002. PMID: 36702649
Preventing allergies through the skin.
Winslow A, Keet CA
Ann Allergy Asthma Immunol 2022 Sep;129(3):276-285. Epub 2022 Apr 22 doi: 10.1016/j.anai.2022.04.013. PMID: 35470039
Allergic Rhinitis in Children and Adolescents.
Schuler Iv CF, Montejo JM
Pediatr Clin North Am 2019 Oct;66(5):981-993. Epub 2019 Aug 5 doi: 10.1016/j.pcl.2019.06.004. PMID: 31466686
Immunotherapy for pet allergies.
Virtanen T
Hum Vaccin Immunother 2018 Apr 3;14(4):807-814. Epub 2017 Dec 21 doi: 10.1080/21645515.2017.1409315. PMID: 29182437Free PMC Article
Food allergies: the basics.
Valenta R, Hochwallner H, Linhart B, Pahr S
Gastroenterology 2015 May;148(6):1120-31.e4. Epub 2015 Feb 11 doi: 10.1053/j.gastro.2015.02.006. PMID: 25680669Free PMC Article

Prognosis

Air Pollution and Noncommunicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 2: Air Pollution and Organ Systems.
Schraufnagel DE, Balmes JR, Cowl CT, De Matteis S, Jung SH, Mortimer K, Perez-Padilla R, Rice MB, Riojas-Rodriguez H, Sood A, Thurston GD, To T, Vanker A, Wuebbles DJ
Chest 2019 Feb;155(2):417-426. Epub 2018 Nov 9 doi: 10.1016/j.chest.2018.10.041. PMID: 30419237Free PMC Article
Vaccination and allergy: EAACI position paper, practical aspects.
Nilsson L, Brockow K, Alm J, Cardona V, Caubet JC, Gomes E, Jenmalm MC, Lau S, Netterlid E, Schwarze J, Sheikh A, Storsaeter J, Skevaki C, Terreehorst I, Zanoni G
Pediatr Allergy Immunol 2017 Nov;28(7):628-640. Epub 2017 Oct 10 doi: 10.1111/pai.12762. PMID: 28779496
Asthma.
Holgate ST, Wenzel S, Postma DS, Weiss ST, Renz H, Sly PD
Nat Rev Dis Primers 2015 Sep 10;1(1):15025. doi: 10.1038/nrdp.2015.25. PMID: 27189668Free PMC Article
Food allergies: the basics.
Valenta R, Hochwallner H, Linhart B, Pahr S
Gastroenterology 2015 May;148(6):1120-31.e4. Epub 2015 Feb 11 doi: 10.1053/j.gastro.2015.02.006. PMID: 25680669Free PMC Article
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351

Clinical prediction guides

Air Pollution and Noncommunicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 2: Air Pollution and Organ Systems.
Schraufnagel DE, Balmes JR, Cowl CT, De Matteis S, Jung SH, Mortimer K, Perez-Padilla R, Rice MB, Riojas-Rodriguez H, Sood A, Thurston GD, To T, Vanker A, Wuebbles DJ
Chest 2019 Feb;155(2):417-426. Epub 2018 Nov 9 doi: 10.1016/j.chest.2018.10.041. PMID: 30419237Free PMC Article
Vaccination and allergy: EAACI position paper, practical aspects.
Nilsson L, Brockow K, Alm J, Cardona V, Caubet JC, Gomes E, Jenmalm MC, Lau S, Netterlid E, Schwarze J, Sheikh A, Storsaeter J, Skevaki C, Terreehorst I, Zanoni G
Pediatr Allergy Immunol 2017 Nov;28(7):628-640. Epub 2017 Oct 10 doi: 10.1111/pai.12762. PMID: 28779496
Predicting asthma outcomes.
Sears MR
J Allergy Clin Immunol 2015 Oct;136(4):829-36; quiz 837. doi: 10.1016/j.jaci.2015.04.048. PMID: 26449797
Food allergies: the basics.
Valenta R, Hochwallner H, Linhart B, Pahr S
Gastroenterology 2015 May;148(6):1120-31.e4. Epub 2015 Feb 11 doi: 10.1053/j.gastro.2015.02.006. PMID: 25680669Free PMC Article
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351

Recent systematic reviews

Prevalence of allergic sensitization with vernal keratoconjunctivitis: A systematic review with meta-analyses.
Rasmussen MLR, D'Souza M, Topal DG, Gradman J, Larsen DA, Lehrmann BB, Kjaer HF, Kessel L, Subhi Y
Acta Ophthalmol 2023 Feb;101(1):9-21. Epub 2022 Jul 18 doi: 10.1111/aos.15212. PMID: 35848379Free PMC Article
Dietary factors during pregnancy and atopic outcomes in childhood: A systematic review from the European Academy of Allergy and Clinical Immunology.
Venter C, Agostoni C, Arshad SH, Ben-Abdallah M, Du Toit G, Fleischer DM, Greenhawt M, Glueck DH, Groetch M, Lunjani N, Maslin K, Maiorella A, Meyer R, Antonella M, Netting MJ, Ibeabughichi Nwaru B, Palmer DJ, Palumbo MP, Roberts G, Roduit C, Smith P, Untersmayr E, Vanderlinden LA, O'Mahony L
Pediatr Allergy Immunol 2020 Nov;31(8):889-912. Epub 2020 Aug 6 doi: 10.1111/pai.13303. PMID: 32524677Free PMC Article
Prenatal vitamin D status and respiratory and allergic outcomes in childhood: A meta-analysis of observational studies.
Pacheco-González RM, García-Marcos L, Morales E
Pediatr Allergy Immunol 2018 May;29(3):243-253. Epub 2018 Mar 8 doi: 10.1111/pai.12876. PMID: 29444346
Atopy and current intestinal parasite infection: a systematic review and meta-analysis.
Feary J, Britton J, Leonardi-Bee J
Allergy 2011 Apr;66(4):569-78. Epub 2010 Nov 18 doi: 10.1111/j.1398-9995.2010.02512.x. PMID: 21087217
BCG vaccination and allergy: a systematic review and meta-analysis.
Arnoldussen DL, Linehan M, Sheikh A
J Allergy Clin Immunol 2011 Jan;127(1):246-53, 253.e1-21. Epub 2010 Oct 8 doi: 10.1016/j.jaci.2010.07.039. PMID: 20933258

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